Saffron Extract Prevents Vancomycin-induced Nephrotoxicity
نویسندگان
چکیده
منابع مشابه
9 Vancomycin - Induced Nephrotoxicity
Nephrotoxicity associated with vancomycin administration has been a topic of debate for over five decades (Tables 1 & 2). Vancomycin is a glycopeptide antibiotic excreted by the kidney and has been used extensively, especially for methicillin-resistant staphylococcus aureus (MRSA) and for many strains of pathogenic staphylococcus epidermis. The nephrotoxic potential of vancomycin is neither ful...
متن کاملReply to "Vancomycin-induced nephrotoxicity".
S. J. van Hal, D. L. Paterson, T. P. Lodise Department of Microbiology & Infectious Diseases, Royal Prince Alfred Hospital, Sydney, Australia; Antibiotic Resistance & Mobile Elements Group, Microbiology and Infectious Diseases Unit, School of Medicine, University of Western Sydney, Sydney, Australia; University of Queensland Centre for Clinical Research (UQCCR), Herston, Australia; Albany Colle...
متن کاملSaffron administration prevents selenite-induced cataractogenesis
PURPOSE The present study sought to investigate whether Crocus sativus stigmas (saffron) extract prevents selenium-induced cataractogenesis in vivo, and to study its possible protective mechanism. METHODS Wistar rat pups were randomized into three groups. Group I (control) received subcutaneous injection of normal saline on postnatal day 10. Groups II (selenite-treated) and III (selenite+saff...
متن کاملThe Nephrotoxicity of Vancomycin
Vancomycin use is often associated with nephrotoxicity. It remains uncertain, however, to what extent vancomycin is directly responsible, as numerous potential risk factors for acute kidney injury frequently coexist. Herein, we critically examine available data in adult patients pertinent to this question. We review the pharmacokinetics/pharmacodynamics of vancomycin metabolism. Efficacy and sa...
متن کاملIncidence and Predisposing Factors of Vancomycin-Induced Nephrotoxicity in Children
INTRODUCTION To investigate the pattern of vancomycin-associated nephrotoxicity in children and to examine potential predisposing factors for nephrotoxicity, including average serum trough concentrations ≥10 μg/mL. METHODS Patients ≥1 week old to ≤15 years with normal baseline serum creatinine values who received vancomycin for ≥48 h between October 2010 and September 2012 were retrospectivel...
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ژورنال
عنوان ژورنال: Imaging in Medicine
سال: 2019
ISSN: 1755-5191
DOI: 10.14303/imaging-medicine.1000129